Van Raamsdonk Lab

Department of Medical Genetics, Life Sciences Institute

Van Raamsdonk, C.D. - Publications

Urtatiz, O, and Van Raamsdonk CD. (2016). Gnaq and Gna11 in the Endothelin signaling pathway and melanoma. Frontiers in Genetics 7: 59.

Huang JL, Urtatiz O, Van Raamsdonk CD. (2015). Oncogenic G protein GNAQ induces uveal melanoma and intravasation in mice. Cancer Research. Aug 15; 75(16):3384-97.

Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, Parkinson DB, Stemmer-Rachamimov AO, Van Raamsdonk CD, Riccardi VM, Rosser T, Schindeler A, Smith MJ, Stevenson DA, Ullrich NJ, van der Vaart T, Weiss B, Widemann BC, Zhu Y, Bakker AC, Lloyd AC. (2014). Update from the 2013 International Neurofibromatosis Conference. Am J Med Genet A. Dec;164A(12):2969-78.

Van Raamsdonk, C. D., and Deo, M. (2013). Links between Schwann cells and melanocytes in development and disease. Pigment Cell and Melanoma Research 26, 634-45.

Levasseur, S. D., Paton, K. E., Van Raamsdonk, C. D., Heran, M. K., and White, V. A. (2013). Mutation of GNAQ in a cytologically unusual choroidal melanoma in an 18-month-old child. JAMA Ophthalmology 131, 810-2.

Deo, M., Huang, J. L., and Van Raamsdonk, C. D. (2013). Genetic interactions between neurofibromin and endothelin receptor B in mice. PLoS One 8, e59931.

Deo, M., Huang, J. L., Fuchs, H., De Angelis, M. H., and Van Raamsdonk, C. D. (2013). Differential effects of neurofibromin gene dosage on melanocyte development. Journal of Investigative Dermatology 133, 49-58.

Tharmarajah, G., Faas, L., Reiss, K., Saftig, P., Young, A., and Van Raamsdonk, C. D. (2012). Adam10 haploinsufficiency causes freckle-like macules in Hairless mice. Pigment Cell and Melanoma Research 25, 555-65.

Van Raamsdonk, C. D., Griewank, K. G., Crosby, M. B., Garrido, M. C., Vemula, S., Wiesner, T., Obenauf, A. C., Wackernagel, W., Green, G., Bouvier, N., et al. (2010). Mutations in GNA11 in uveal melanoma. New England Journal of Medicine 363, 2191-9.

Van Raamsdonk, C. D. (2009). Hereditary hair loss and the ancient signaling pathways that regulate ectodermal appendage formation. Clinical Genetics 76, 332-40.

Van Raamsdonk, C. D., Barsh, G. S., Wakamatsu, K., and Ito, S. (2009). Independent regulation of hair and skin color by two G protein-coupled pathways. Pigment Cell and Melanoma Research 22, 819-26.

Van Raamsdonk, C. D., Bezrookove, V., Green, G., Bauer, J., Gaugler, L., O'brien, J. M., Simpson, E. M., Barsh, G. S., and Bastian, B. C. (2009). Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature 457, 599-602.

Van Raamsdonk, C. D., Fitch, K. R., Fuchs, H., De Angelis, M. H., and Barsh, G. S. (2004). Effects of G-protein mutations on skin color. Nature Genetics 36, 961-8.

Candille, S. I., Van Raamsdonk, C. D., Chen, C., Kuijper, S., Chen-Tsai, Y., Russ, A., Meijlink, F., and Barsh, G. S. (2004). Dorsoventral patterning of the mouse coat by Tbx15. PLoS Biology 2, E3.

Fitch, K. R., Mcgowan, K. A., Van Raamsdonk, C. D., Fuchs, H., Lee, D., Puech, A., Herault, Y., Threadgill, D. W., Hrabe De Angelis, M., and Barsh, G. S. (2003). Genetics of dark skin in mice. Genes and Development 17, 214-28.

Cleary, M. A., Van Raamsdonk, C. D., Levorse, J., Zheng, B., Bradley, A., and Tilghman, S. M. (2001). Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice. Nature Genetics 29, 78-82.

Van Raamsdonk, C. D., and Tilghman, S. M. (2001). Optimizing the detection of nascent transcripts by RNA fluorescence in situ hybridization. Nucleic Acids Research 29, E42-2.

Van Raamsdonk, C. D., and Tilghman, S. M. (2000). Dosage requirement and allelic expression of PAX6 during lens placode formation. Development 127, 5439-48.